What is Botox?

Botox toxin is a protein made by bacterium Clostridium botulinumand shall be deemed the most powerful neurotoxin ever discovered. Botulinum toxin causes botulism poisoning, significant and life-threatening disease in humans and animals. When intravenously into monkeys, type A (Botox Cosmetic) toxins artifacts LD50 40-56 ng, such as about 32 ng of C1, type D 3200 ng, and type E 88 ng, providing these kinds of some the most powerful neurotoxin known. A well-known one of its brand name, Botox or Dysport, it is used for different cosmetic and medical procedures.

Proteins are used in cosmetic medicine for the treatment of so-called phenomenon of "Lazy Eye" uncontrolled blinks, wrinkles and folds face. For these procedures uses a small amount of diluted botulinum toxin that controls muscle weakness

Important information about Botox

Contained in Botox Botulinum toxin may also spread to other parts of the body, it can cause number of serious side effects, even among those people who have used Botox for cosmetic purposes.

The use of Botox often than prescribed will not make it more efficient and can lead to devastating side effects.

Some side effects may occur for several weeks after the injection of Botox. If you have: hoarse voice, lowered eyelids, loss bladder control, vision problems, difficulty breathing or muscle weakness, call your doctor.

The effects of a Botox injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.

Botox injections should be performed only by qualified specialist, even when used for cosmetic purposes.

Before the injection of Botox, tell your doctor if you have a disease ALS (Lou Gehrig's disease), myasthenia gravis, Lambert-Eaton syndrome, respiratory failure, problems with swallowing, facial muscle weakness, heart disease, changing the look of your face, bleeding problems , cramps, if you have had surgery or will be, or if you ever get the other Botox, such as Dysport or Myobloc.

Before I receive Botox

You should not use Botox if you are allergic to botulinum toxin, or if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected. Tell your doctor if you have ever had the side effect after use of Botox in the past.

If you have any of these other conditions, you may need a dose adjustment or special tests:

• amyotrophic lateral sclerosis (ALS, or "Lou Gehrig\'s disease");
• myasthenia gravis;
• Lambert-Eaton syndrome;
• a breathing disorder such as asthma or emphysema;
• problems with swallowing;
• facial muscle weakness (droopy eyelids, weak forehead, trouble raising your eyebrows);
• a change in the normal appearance of your face;
• a seizure disorder;
• bleeding problems;
• heart disease;
• if you have had or will have surgery (especially on your face); or
• if you have ever received other Botox injections such as Dysport or Myobloc (especially in the last 4 months).

How is Botox given?

BOTOX®Cosmetic is to be reconstituted only with 0.9% sterile, non-preserved saline prior to intramuscularinjection. Per the dilution table below, draw up the required amount of 0.9% sterile non-preserved sodium chloride solution into a syringe to obtain a reconstituted solution at a concentration of 4 Units/0.1 mL and a total treatment dose of 20 Units in 0.5 mL. The duration of activity of BOTOX®Cosmetic for glabellar lines is approximately 3-4 months. The safety and effectiveness of more frequent dosing with BOTOX®Cosmetic has not been clinically evaluated and is not recommended.

Dilution Table

The use of of Botox more frequently than prescribed will not make it more effective and can result in severe side effects.

What happens if I miss a dose?

Botox has side effects if the dose does not produce on time.

What happens if I overdose?

Overdose Symptoms may not be shown right now, but may include muscle weakness, problems with swallowing, and weak or shallow breathing time. If you feel these symptoms contact a doctor immediately.

What should I avoid after receiving Botox?

Botox can cause a deterioration in the perception and vision. If you are driving or doing or anything requiring sharp vision, be careful!

After Botox injections in 24 hours refrain from using antiperspirant and deodorants.

Avoid physical activity if you have recently had an injection of Botox

Botox side effects

Tell your doctor about all your medical conditions, including if you:

Who should not take BOTOX or BOTOX Cosmetic?

Do not use BOTOX© or BOTOX® Cosmetic if you:

• Make are that you are not allergic to any of the ingredients in BOTOX© or BOTOX® Cosmetic. See the end of this Medication Guide for a list of ingredients in BOTOX and BOTOX Cosmetic.
• had an allergic reaction to any other botulinum toxin product such as Myobloc®, Dysport®, or Xeomin®
• have a skin infection at the planned injection place
• are being treated for enuresis and have a urinary tract infection (UTI)
• have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig\'s disease], myasthenia gravis or Lambert-Eaton syndrome).
• have allergies to any Botox product
• had any side effect from any Botox product in the past
• have or have had a breathing problem, such as asthma or emphysema
• have or have had swallowing problems
• have or have had bleeding problems
• have plans to have surgery
• had surgery on your face
• have weakness of your forehead muscles, such as trouble raising your eyebrows
• have drooping eyelids
• have any other change in the way your face normally looks
• have symptoms of a urinary tract infection (UTI) and are being treated for urinary incontinence. Symptoms of a urinary tract infection may include pain or burning with urination, frequent urination, or fever.
• have problems emptying your bladder on your own and are being treated for urinary incontinence
• are pregnant or plan to become pregnant. It is not known if BOTOX or BOTOX Cosmetic can harm your unborn baby.
• are breast-feeding or plan to breastfeed. It is not known if BOTOX or BOTOX Cosmetic passes into breast milk.

What other drugs will affect Botox?

Tell your doctor about all other medicines you may use, especially:

administered antibiotics such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), paromomycin (Humatin, Paromycin), streptomycin, tobramycin (Nebcin, Tobi).

This list is not complete and there may be other drugs that can interact with Botox. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Don`t start a new medication without telling your doctor.